Generic Zyban (Bupropion)
Zyban is an atypical antidepressant which helps to stop smoking by reducing cravings and withdrawals.
Per Pills
150 mg x 30 pills
150 mg x 60 pills
150 mg x 90 pills
150 mg x 120 pills
150 mg x 240 pills
Product Description
You should not take Zyban if you have seizures, an eating disorder, or if you have suddenly stopped using alcohol, seizure medication, or sedatives. Zyban dosage information in more detail. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive mentally or physicallymore depressed, or have thoughts about suicide or hurting yourself. Blood pressure sometimes goes up in people who take bupropion. Take the missed dose as soon as you remember. Do not smoke at any time if you are using a nicotine product along with Zyban. See also: Zyban drug interactions in more detail. Pediatric Treatment Editorial Board. These changes can include nervousness, difficulty concentrating, hostility, agitation, depressed mood and suicidal thoughts or actions. Stop Chantix and seek emergency medical care if this occurs. You may not be allowed to take these medications or you may need a lower dose. The two drugs are not interchangeable. It is very Zyban to talk about this with your doctor. Do not smoke at any time if you are using a nicotine product along with Zyban. These effects should be mild and often disappear after a few weeks. How do I take bupropion? You should stop taking Chantix and contact your healthcare provider immediately if you develop agitation, hostility, depressed mood, or changes in behavior or thinking that are not typical, or if you experience suicidal thoughts. Thanks for your feedback! Call to get started. Tegretol carbamazepineNeurontin gabapentinLamictal lamotriginePhenobarbital, Dilantin phenytoinTrileptal oxcarbazepineTopamax topiramateDepakote divalproex sodium. Read all directions and safety information for the nicotine product. If you wish to report a side-effect, you will need to provide basic information about: The side-effect. Intramural Research. Research Program Contacts. Cahill K, Stevens S, Perera R, et al ; Pharmacological interventions for Zyban cessation: an overview and network meta-analysis. Tell your doctor if you have any side effect that bothers you or that does not go away. Screening Tests. Brand name listings. Journal of Affective Disorders. Cancer Treatment Research. Symptoms are more likely to occur early in the treatment. E-cigarettes: an evidence update ; Public Health England, August IC 50 4. Explore other support options There are a range of support options available to help you quit. If you are not sure you can quit, you can take a gradual approach with Chantix by cutting the number of cigarettes you smoke per day in half the first four weeks, and then cut that in half again for the next four weeks and so on until you can go smoke-free at 12 weeks. Urquhart DM ed. Bupropion and bupropion analogs as treatments for CNS disorders. The recommended course of treatment is 7 weeks, but it can be taken for a longer period of time.

Zyban - really surprises

To illustrate, they cited significant differences in the reported rates of adverse reactions and deaths attributed to Zyban buproprion in Canada and the United Kingdom. Epub May 2. These are identified in the product information. Questions to Ask about Your Treatment. Zyban increases the levels of the chemicals dopamine, serotonin, and norepinephrine in the brain. Having a history of mental health issues, including depression, bulimia or alcohol abuse. Various Zjban have looked at this issue. Article Sources. Zybaan this article Smoking and nicotine addiction What is bupropion and how does it work. Recent Public Laws. Cancer Treatment Research. Transfer of a Grant. Late Effects of Childhood Cancer Treatment. Childhood Cancers Research. Taking certain medications, especially taking or abruptly stopping monoamine oxidase inhibitors MAOIsmedications used to treat depression or Parkinson's disease, bulimia, and anorexia nervosalinezolid, intravenous methylene blue, antiepileptic drugs or Wellbutrin. You use any other drug containing bupropion hydrochloride You have or have had a seizure disorder You have or have had an eating disorder You are taking or have recently taken a monoamine oxidase inhibitor MAOI You are pregnant or nursing You are allergic to bupropion hydrochloride You are abruptly discontinuing alcohol or sedatives including benzodiazepines. Action on Smoking and Health. Too much of this medicine can increase your risk of a seizure. While this medication was developed as an anti-depressant, you do not need to suffer from depression for it to work as a quit aid. Subsequently, the risk of Zybann was found to be Zyhan dose-dependent, and bupropion was re-introduced to the market in with a lower maximum recommended daily dose. Your doctor will need to check your progress at regular visits while you are using Zyban. In the UK, more than 7, reports of suspected adverse reactions were collected in the first two years after bupropion's approval by the Medicines and Healthcare Products Regulatory Agency as part of the Yellow Card Schemewhich monitored side effects. This medication comes in tablet form and is usually taken 2 times a day, with or without food. The primary metabolite, hydroxybupropion has the same effect as bupropion to block noradrenaline and dopamine re-uptake, so it extends the drug's duration of action. Zyban Precautions Back to Top. When Chantix was studied in combination Zybn nicotine replacement Zybqn, the incidence of side effects such as nausea, headache, vomiting, dizziness, indigestion, and fatigue, was much higher than with nicotine alone. Some people taking Zyban have had high blood pressure that is severe, especially when also using a nicotine replacement product patch or gum. Read the packet leaflet for a full list of possible side-effects and cautions. Late Effects of Childhood Cancer Ztban. Since dopamine is inactivated by norepinephrine reuptake in the frontal cortex, which largely lacks dopamine transporters, bupropion can increase dopamine neurotransmission in this part of the brain. Quitting Smoking, Quit-Smoking Medications, Changes in Thinking and Behavior, Depression, and Suicidal Thoughts or Actions Some people have had changes in behavior, hostility, agitation, depression, suicidal thoughts or actions while taking Zyban to help them quit smoking. Bupropion is less likely than other antidepressants to cause sexual dysfunction. Ascent Pharma Pty Ltd. Zyban bupropion Hcl Er is available in generic, as mg extended-release tablets. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive mentally or physicallymore depressed, or have thoughts about suicide or hurting yourself. Drinking alcohol with bupropion may increase your risk of seizures. Nicotine replacement therapy NRT : frequently asked questions There are heaps of quitting options and methods out there. Archived from the original on 28 September Skip to Content. This warning is based on a statistical analysis conducted by the FDA which found a 2-fold increase in suicidal thought and behavior in children and adolescents, and 1. The addition to a prescribed SSRI is a common strategy when people do not respond to the SSRI, even though this is not an officially approved indication. Advisory Boards and Review Groups. Here are more warnings associated with Chantix: Risk of hypersensitivity or angioedema, which is swelling of the face, mouth, tongue, lips, and gumsextremities, and neck.

Common use

Zyban is an antidepressant medicine which used for helping certain patients to stop smoking cigarettes. Zyban booststhe levels of several chemical messengers in the brain, so you experience a reduction in nicotine withdrawal symptoms and a weakening of the urge to smoke.

Dosage and direction

If you take Zyban to help you stop smoking, you may continue to smoke for about seven days after you start to use Zyban.

The medication can be taken discreetly, so no one but your doctor needs to know you are using it. Take it oral with or without food. Swallow this medication whole.

Common prescribed dosing for Zyban is 300 mg/day, given as 150 mg, twice daily. There should be an interval of at least 8 hours between successive Zyban doses.

Also you may use nicotine patches or gum to help support your smoking cessation treatment.

Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It help you to get best results.


Do not use it if you are allergic to any ingredient in Zyban. Do not use this medication if you are pregnant, intend to become pregnant or breastfeeding. Do not use it if you are taking any other medicine that contains bupropion. Do not smoke if you are using this medication along with the nicotine skin patch or any nicotine product. Also note that using Zyban and nicotine patches together may raise your blood pressure.


Tell your doctor about prescription medication you take including: MAO inhibitors, levodopa, theophylline, corticosteroids, seizure medications, sedatives, antivirals, tranquilizers/psychiatric drugs, other antidepressants, benzodiazepines , salicylates, isoniazid, chlolinesterase inhibitors, morphine, and adrenaline-like drugs, opiates, cocaine, or stimulants, diabetes medications, etc. Note that caffeine intake can increase the chance of seizures with this drug.

Possible side effects

The most usual side effects are dry mouth and difficulty sleeping. Inform your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Drug interactions

Do not take Zyban if you have taken a monoamine oxidase inhibitor such as phenelzine, isocarboxazid , or tranylcypromine in the last 14 days. There are also many medications that may interact with Zyban, including but not limited to: Amantadine, antipsychotics, corticosteroids, Insulin, Levodopa, Carbamazepine, Phenobarbital, Antiarrhythmics, Beta-blockers and other antidepressants. Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

Missed dose

If you have forgotten to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.


Symptoms of a Zyban overdose include seizures, loss of consciousness, weakness, hallucinations, a fast heartbeat, and heart attack. Immediately call your doctor if you experience on of them.


Store at room temperature between 20-25 C (68-77 F).


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Thyroid problems

Thyroid gland a gland of the organism located in the front part of the neck. The whole gland weights 25-30g. It works by producing 4 hormones amongst which the major are T4 Thyroxin and T3 Tri-iodothyronine. Also the gland produces Calcitonin a biologically active substance that regulates the Ca2+ metabolism in the body.

The thyroid gland, pituitary gland and hypothalamus work as one regulatory system. There are different types of thyroid gland dysfunctions for example:

  • Hypothyroidism A dysfunction which manifests in decreased production or inability to produce thyroid hormones. All the metabolism processes in the organism are slowed down. The causes of the disorder might be autoimmune thyroiditis, therapy with radioactive Iodine, hereditary disorders.
  • Hyperthyroid an excess in production of thyroid hormones. The disorder leads to an increase in the organisms metabolism speed. The causes of the disorder might be: benign tumors, when the gland is not controlled by the pituitary gland, autoimmune processes Graves's disease. The symptoms of the hyperfunction may lead to thyrotoxic crisis or thyroid storm a severe condition which affects the main organism functions and in turn may leading to coma and death.
  • Another dysfunction of the thyroid gland is goiter which is caused by iodine insufficiency, followed by an increase in size of the thyroid gland which may lead to hyper- or hypothyroidism.

If you feel that some of the following may be applied to youthen a possibility of the thyroid disorder exists:

  • Fatigue, especially in the morning and less in the evening
  • Changes in weight, especially around the abdomen
  • Depression and melancholy
  • Increased levels of cholesterol
  • Spasms and muscle contractions
  • Constipation
  • Arthritis and joint pain
  • Bad memory and other neurological

All of the above may signal a possible thyroid disorder. It would be safe to consult your doctor and measure the levels of the T4 and T3 hormones in the blood.