Generic Zocor (Simvastatin)
Zocor
Zocor is a cholesterol- lowering medication prescribed to inhibit the production of cholesterol by the liver.
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Product Description

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Zocor - something is

If you become pregnant and you are on it, it should be stopped. A: The pharmacological effects of Zocor simvastatin are demonstrated in the inhibition of cholesterol production in the body. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. Many drugs can interact with simvastatin. Although typical doses used to treat your lipids range from 5 to 40 mg, your healthcare provider may start you on a lower dose and slowly increase your dose, based upon your LDL levels and your response to the medication.

Zocor - seems brilliant

Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do Zocor understand. Retrieved 12 July Your doctor will probably tell you not to take Zcoor if you are taking these medications. If you're still not meeting LDL goals, one tactic is to crank up the statin dose Zocro the usual 10—40 milligrams mg daily to an "aggressive" 80 mg. Views Read Edit View history. The biochemistry of nitric oxide, nitrite, and hemoglobin: role in blood flow regulation. The New York Times. Always speak with your doctor or pharmacist about dosages that are right for you. Consuming large amounts of grapefruit juice increases serum levels of simvastatin by up to three-fold, increasing the risk of side effects. N Engl J Med. When taken with warfarin, simvastatin can increase the blood-thinning effects of warfarin. Taking no more than the recommended dose of simvastatin with these medications will help keep simvastatin levels in the body at a safer level. I accept the Terms and Privacy Policy. Drug Class. Drug Status Rx. These interactions are clinically important because increasing simvastatin serum levels above those normally provided by the maximum recommended dose increases the risk of muscle damage, including the otherwise rare and potentially fatal side effect of rhabdomyolysis. The most serious form of myopathy, called rhabdomyolysis, can damage the kidneys and lead to kidney failure which can be fatal. No Preference. If you are planning to become pregnant or are already pregnant and are taking Zocor, Zockr healthcare provider will weigh the benefits of taking the medication on your health and Zicor possible Zocor to your child. However, if you eat a diet high in fat, your body may not keep this balance and your cholesterol levels rise. Liver problems can also occur and may be serious. At these doses the only signs seen in dogs were emesis and mucoid stools. The maximum recommended daily dose in adolescents is 40 mg. If you think that you are experiencing a side effect from your Zocor, the recommendation is made to talk to your physician. Should you change a medication after you have taken it for several years? Q: I Zcor been on Zocor 40 mg a day Zocpr years. Its structural formula is:. Discuss Zoclr pregnancy plans with your patients, and discuss when to stop taking Zoco if they are trying to conceive. Zocpr statins act by inhibiting 3-hydroxymethylglutaryl HMG coenzyme A reductase. The breakdown of the muscle can lead to severe kidney damage and possible kidney failure. General Information About Livalo Pitavastatin. Zocor dosage information Zockr more detail. If you are considering pregnancy, you should consider stopping Zocor. This is because on rare occasions, muscle problems can be serious, including muscle breakdown resulting in kidney damage that can lead to death. The development of simvastatin was closely linked with lovastatin. Can the medication cause this? Talk to your doctor, pharmacist, or dietician about these measures and for more information. Upper respiratory infection, headache, abdominal pain, constipation, nausea, elevated serum transaminases, myopathy, rhabdomyolysis; increased HbA1c and fasting serum glucose, rare: cognitive impairment, non-fatal hepatic failure, immune-mediated necrotizing myopathy. In another week study, simvastatin mg had no detectable effect on spermatogenesis. Zocor is indicated to reduce the risk of mortality by reducing deaths resulting from coronary heart disease and reduced the risk of heart attack and stroke in high risk patients. As a result of the gastrointestinal adverse reactions associated with treatment, patients may lose weight. One man shares how - and why - he learned to meditate even though he…. While you take simvastatin, your doctor will want to make sure that it isn't affecting your liver and kidneys. Could I possibly be having an allergic reaction, hence the itching? I am having a problem urinating since I started Zocor. Food and Drug Administration, these products are not required to be tested for effectiveness, purity, or safety. Extramural Research. I am taking 40 mg of Zocor, and read a study that suggests decreasing that amount and supplementing with coenzyme Q10 would be very beneficial to counter the side effects of the Zocor. Retrieved 19 July Strategic Planning. Grapefruit and grapefruit juice interact with Zocor and may increase a patients risk for adverse reactions. For that reason, be sure to tell your doctor about any prescription, non-prescription, over-the-counter OTCillegal and recreational drugs, herbal remedies, nutritional and dietary supplements, and all other drugs and treatments you're taking. Increased rhabdomyolysis with concomitant daptomycin; suspend simvastatin temporarily. Pediatric Treatment. Remember, keep this and all other medicines out Zocor the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Strong CYP3A4 inhibitors e. Simvastatin side effects. Merck: Whitehouse Station, NJ. Simvastatin is contraindicated with pregnancy, breastfeeding, and liver disease. Drug treatment also significantly increased the incidence of lung adenomas in mid- and high-dose males and females. Do not use if you are pregnant or planning to become pregnant.
Common use

Zocor is a cholesterol-lowering medication which used to treat high cholesterol levels in the blood. It works by blocking the production of cholesterol in the body, thus can help prevent conditions that can lead to heart attack, heart disease and hardening of the arteries, stroke, and vascular disease. This medication can also reduce these risks in people with diabetes, peripheral vascular disease, and a history of stroke. Use this medication during low fat diet to get the best result.



Dosage and direction

Take this medication orally with or without food/milk.

The recommended starting dose of Zocor for adults is 20 to 40 milligrams once a day in the evening. The dosage can be varied every 4 weeks.

The recommended starting dose for children 10 to 17 years old is 10 milligrams once a day in the evening. The dosage can be varied every 4 weeks, but should not exceed 40 mg a day. Girls must have been menstruate for at least 12 months before starting therapy with Zocor.

Children under 10 years old only after doctor permission.

Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It help you to get best results.



Precautions

Before taking Zocor consult with your doctor if your medical history include: history of alcoholism, liver disease, severe infection, kidney disease, low thyroid function, heart disease, allergies. Try to limit alcohol intake because it can increase side effects. Also note: Zocor may increase your risk for liver problems. During the treatment with Zocor you may to limit the amount of grapefruit or grapefruit juice you may eat or drink (less than 1 quart a day) , because grapefruit juice may increase your risk for serious side effects.

For woman: Zocor should not be used during pregnancy, becoming pregnancy or lactating. Do not use before breast-feeding without doctor's permission.



Contraindications

Zocor is not allowed in patients with active liver disease or unexplained persistent elevations of serum transaminases or who are hypersensitivity to any component of this medication. Pregnancy and lactation. Atherosclerosis is a chronic process and the discontinuation of lipid-lowering medications during pregnancy should have little impact on the outcome of long-term therapy of primary hypercholesterolemia. Ability of inhibitors of HMG-CoA reductase such as Zocor can decrease the synthesis of cholesterol and possibly other products of the cholesterol biosynthesis pathway, so Zocor is contraindicated during pregnancy and in nursing mothers. Zocor should be administered to women of childbearing age only when such women are highly unlikely to become pregnant. If the patient conceve while taking this drug, Zocor should be discontinued immediately and the patient should be apprised of the potential hazard to the fetus



Possible side effect

They may include all types of an allergic reaction. Also the most possible side effects include:

muscle pain, tenderness, or weakness with fever or flu symptoms and dark colored urine.

Less serious include:

mild stomach pain, gas, bloating, stomach upset, heartburn;

nausea;

constipation; or

diarrhea.

If you experience one of them stop using Serevent and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.



Drug interaction

Zocor interact with such types of drugs as: danazol; gemfibrozil (Lopid), clofibrate, or fenofibrate;

niacin; nefazodone; cholestyramine or colestipol; warfarin; amiodarone, diltiazem, or verapamil;

erythromycin, clarithromycin, or telithromycin; an antifungal medication such as itraconazole, fluconazole, or ketoconazole; drugs that weaken your immune system such as cancer medicine or steroids, cyclosporine, sirolimus, tacrolimus, and others; HIV or AIDS medication such as amprenavir, indinavir, nelfinavir, ritonavir, lopinavir-ritonavir, or saquinavir. Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.



Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.



Overdose

Overdose of Zocor is not danger for you life and iclude such symptoms: myalgia and red urine (in a severe overdose). If you experience one of them call your doctor immediately.



Storage

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Thyroid problems

Thyroid gland a gland of the organism located in the front part of the neck. The whole gland weights 25-30g. It works by producing 4 hormones amongst which the major are T4 Thyroxin and T3 Tri-iodothyronine. Also the gland produces Calcitonin a biologically active substance that regulates the Ca2+ metabolism in the body.

The thyroid gland, pituitary gland and hypothalamus work as one regulatory system. There are different types of thyroid gland dysfunctions for example:

  • Hypothyroidism A dysfunction which manifests in decreased production or inability to produce thyroid hormones. All the metabolism processes in the organism are slowed down. The causes of the disorder might be autoimmune thyroiditis, therapy with radioactive Iodine, hereditary disorders.
  • Hyperthyroid an excess in production of thyroid hormones. The disorder leads to an increase in the organisms metabolism speed. The causes of the disorder might be: benign tumors, when the gland is not controlled by the pituitary gland, autoimmune processes Graves's disease. The symptoms of the hyperfunction may lead to thyrotoxic crisis or thyroid storm a severe condition which affects the main organism functions and in turn may leading to coma and death.
  • Another dysfunction of the thyroid gland is goiter which is caused by iodine insufficiency, followed by an increase in size of the thyroid gland which may lead to hyper- or hypothyroidism.

If you feel that some of the following may be applied to youthen a possibility of the thyroid disorder exists:

  • Fatigue, especially in the morning and less in the evening
  • Changes in weight, especially around the abdomen
  • Depression and melancholy
  • Increased levels of cholesterol
  • Spasms and muscle contractions
  • Constipation
  • Arthritis and joint pain
  • Bad memory and other neurological

All of the above may signal a possible thyroid disorder. It would be safe to consult your doctor and measure the levels of the T4 and T3 hormones in the blood.