Generic Sinemet Cr (Carbidopa / Levodopa)
Sinemet Cr
Sinemet is formulated from two medications: carbidopa and levodopa. It is used relieve symptoms of Parkinson's disease such as the muscle tremor, stiffness, and weakness.
Per Pills
250 mg x 30 pills
250 mg x 60 pills
250 mg x 90 pills
250 mg x 120 pills
250 mg x 180 pills
250 mg x 360 pills
Product Description
Dose advice: How to use Sinemet CR Before you take Sinemet CR When you must not take it Do not take Sinemet CR if: You have an allergy to Sinemet CR or any of the ingredients listed here; You have any unusual skin lumps or moles C have not been examined by your Siemet, or if you have Crr had skin cancer or melanoma; You have a type of glaucoma called narrow-angle glaucoma; Are being treated for depression with certain medicines called monoamine oxidase MAO inhibitors. Therapeutic Class. Suspicious undiagnosed skin lesions or a history of melanoma. Please enable JavaScript for an optimal experience. As this medication is delivered using a pump-tube delivery system, complications can occur from the surgical procedure required to create the small opening in the stomach wall for the intestinal tube and with long-term use of the intestinal tube. Others: see literature. Please be aware that we do not give advice on your individual medical condition, if you want advice please see your treating physician. If symptoms persist see your healthcare professional. May affect ability to drive or operate machines. This loss of movement may last from a few minutes to several hours. Women of childbearing potential. Bioavailability of Sinemet CR levodopa is less than that of standard Sinemet, so a slightly higher total daily levodopa dose is required to achieve a comparable effect; but because Sinemet CR is absorbed much more slowly than is the standard preparation, dosing frequency can be reduced by up to half. Medications other than those listed above may interact with this medication. Have blood tests when your doctor says to make sure Sinemet CR is not causing any problems with your blood, liver, kidneys or heart. About Shop.

Sinemet Cr - think

Active Ingredients Daptomycin. This may help reduce the possibility of withdrawal symptoms such as muscle stiffness, fever Sinemef mental changes. Iloperidone: Major Iloperidone is a central dopamine antagonist and may Sibemet the Sinfmet response to antiparkinsonian agents with dopamine agonist properties by blocking dopamine receptors in the Sinrmet. Sinemet Cr should be observed for signs of neuroleptic malignant syndrome while Sinemmet is interrupted, and the usual levodopa regimen should be administered as soon as the patient is able to take oral medication. Do not crush or chew the medication as this will destroy the time-release property of the medication. Do not be alarmed by this list of possible side effects. Initial dosage should not be given at intervals of less than 6 hours. Medicine Name Elocon Cream. Your doctor may prescribe you a stronger dose of Sinemet CR or may ask you to take it more frequently. Haloperidol: Major Antipsychotic agents may inhibit the clinical antiparkinsonian response to levodopa by blocking dopamine receptors in the brain. Trifluoperazine: Major Phenothiazines may inhibit the clinical antiparkinsonian response to levodopa by blocking dopamine receptors in the brain and levodopa may decrease the response to phenothiazines by increasing central dopamine levels. These behaviours are called impulse control disorders. Additional dose adjustments may be necessary over time based on the patient's level of activity and disease progression. The dose varies considerably from patient to patient. Add 3 mLs to the morning dose to fill prime the intestinal tube to obtain the total morning dose. Current evidence indicates that symptoms of Parkinson's disease are related to depletion of dopamine in the corpus striatum. There is evidence, however, to suggest that amino acid-levodopa transport competition is more likely to occur during levodopa active transport across the blood-brain barrier. Update Thursday, April 18, : This article has been updated to reflect recent information obtained from representatives of Merck Canada Inc. Dosages of levodopa should be reduced 2 to 3 days after beginning selegiline therapy. Others: see literature. Propantheline: Moderate Anticholinergics can potentiate the dopaminergic effects of levodopa. Although this combination appears safe and effective overall, additive neurologic effects are possible. Available for Android and iOS devices. Max: 8 tab daily.
Common use

Sinemet is a combination of carbidopa and levodopa applied in treatment of Parkinson's disease and Dopa-Responsive Dystonia (DRD).

It is also applied in other cases.

Dosage and direction

Apply Sinemet on clean dry face. Spread it evenly over the treated areas of skin. Avoid applying Sinemet on irritated skin.

It may take 6-9 weeks to see the effect.

Turn to your doctor or pharmacist for more details.


Applying Sinemet to your face avoid the areas around your eyes, lips or other sensitive areas.

Inform your doctor if you have eczema, diabetes, glaucoma, any other diseases.

Aged people can be more sensitive to side effects of the medicine.

Inform your doctor if you are pregnant or breast-feed.


Sinemet should not be used by patients having demonstrated a reaction of hypersensitivity to it.

Possible side effects

The most common side effects are redness, scaling, itching, and burning.

A very serious allergic reaction rarely occurs. Many people using this medicine do not have serious side effects.

Turn to your doctor or pharmacist for more details.

In case you notice the effects not listed here, contact your doctor or pharmacist.

Drug interactions

Before taking Sinemet tell your doctor or chemist of all prescription and non-prescription medicines you are taking.

Sinemet should not be used with

* MAO Inhibitors like Nardil, Parnate, Marplan, Eldepryl

* iron supplements.

Turn to your doctor or pharmacist for more details.

Missed dose

If you have missed your dose, take it as soon as you remember. If you see that it is near the time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not take your dose twice.


If you think you have used too much of this medicine seek emergency medical attention right away. The symptoms of overdose usually include chest pain, nausea, irregular heartbeat, and feeling light-headed or fainting.


Store your medicines at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store your drugs in the bathroom. Keep all drugs away from reach of children and pets.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Thyroid problems

Thyroid gland a gland of the organism located in the front part of the neck. The whole gland weights 25-30g. It works by producing 4 hormones amongst which the major are T4 Thyroxin and T3 Tri-iodothyronine. Also the gland produces Calcitonin a biologically active substance that regulates the Ca2+ metabolism in the body.

The thyroid gland, pituitary gland and hypothalamus work as one regulatory system. There are different types of thyroid gland dysfunctions for example:

  • Hypothyroidism A dysfunction which manifests in decreased production or inability to produce thyroid hormones. All the metabolism processes in the organism are slowed down. The causes of the disorder might be autoimmune thyroiditis, therapy with radioactive Iodine, hereditary disorders.
  • Hyperthyroid an excess in production of thyroid hormones. The disorder leads to an increase in the organisms metabolism speed. The causes of the disorder might be: benign tumors, when the gland is not controlled by the pituitary gland, autoimmune processes Graves's disease. The symptoms of the hyperfunction may lead to thyrotoxic crisis or thyroid storm a severe condition which affects the main organism functions and in turn may leading to coma and death.
  • Another dysfunction of the thyroid gland is goiter which is caused by iodine insufficiency, followed by an increase in size of the thyroid gland which may lead to hyper- or hypothyroidism.

If you feel that some of the following may be applied to youthen a possibility of the thyroid disorder exists:

  • Fatigue, especially in the morning and less in the evening
  • Changes in weight, especially around the abdomen
  • Depression and melancholy
  • Increased levels of cholesterol
  • Spasms and muscle contractions
  • Constipation
  • Arthritis and joint pain
  • Bad memory and other neurological

All of the above may signal a possible thyroid disorder. It would be safe to consult your doctor and measure the levels of the T4 and T3 hormones in the blood.