Generic Serophene (Clomiphene)
Serophene is a fertility drug, used to stimulate FSH and LH production and hereby the ovaries to produce eggs in ovarian disorders.
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25 mg x 30 pills
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50 mg x 30 pills
50 mg x 60 pills
50 mg x 90 pills
50 mg x 120 pills
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100 mg x 30 pills
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Product Description
The dose should be increased only in those patients who do not ovulate in response to Seeophene 50 mg clomiPHENE citrate. Other side effects not listed may also occur in some patients. However, prolonged visual disturbances have been reported after clomiPHENE citrate therapy has been discontinued and these disturbances may be irreversible. Discuss with your healthcare professional the use of your Segophene with food, alcohol, or tobacco. Available for Android and iOS devices. Clinical evaluation may reveal hypovolemia, hemoconcentration, electrolyte imbalances, ascites, hemoperitoneum, pleural effusions, hydrothorax, acute pulmonary distress, and thromboembolic phenomena. Also, rhesus monkeys given oral doses of 1. These side effects may go away during treatment as your body adjusts to the medicine. This sharp rise, the LH surge, usually causes ovulation within about 30 hours. For some, it may be so they can get their career off to a good start, or they want to be more financially sound before raising a child. Availability Discontinued. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. Inactive Ingredients. Until the correct diagnosis has been determined, the next course of therapy should be delayed. Please check and try again Agree to Terms required. Clomiphene citrate is designated chemically as 2-[p- 2-chloro-1,2-diphenylvinyl phenoxy] triethylamine dihydrogen citrate and is represented structurally as:. Long-term Serohene therapy is not recommended beyond a total of about six cycles SSerophene three ovulatory cycles. Serophene side effects in Serophene detail. The most frequent adverse reactions to clomiphene citrate include ovarian enlargement approximately 1 in 7 patientsvasomotor flushes Serophnee menopausal symptoms which are not usually severe and promptly disappear after treatment is discontinued approximately 1 in 10 patientsand abdominal discomfort approximately 1 in 15 Serpphene. For non-prescription products, read the label or package ingredients carefully. These side effects may go away during treatment as your body adjusts to the medicine. In women, this causes ovulation to occur and prepares the body for pregnancy. Since the relative safety of long-term cyclic therapy has not yet been demonstrated conclusively, and since the majority of patients will ovulate following 3 courses, long-term cyclic therapy is not recommended. Subscribe to our newsletters. Ovarian enlargement and cyst formation associated with clomiPHENE citrate therapy usually regress spontaneously within a few days or weeks after discontinuing treatment. Symptoms often appear first, or are accentuated, upon exposure to a more brightly lit environment. Due to fragility of enlarged ovaries in severe cases, abdominal and pelvic examination should be performed very cautiously. Table 1 reports the survival rate of the live multiple births.

Serophene - this

Other Laboratory Studies: Clomiphene citrate has not been reported to cause Seropehne significant abnormality in hematologic Seerophene renal tests, in protein bound iodine, or in serum cholesterol levels. Do not use more of this product, or more often, than prescribed. The cumulative rate of congenital abnormalities does not exceed that reported in the general population. Other liver Serophen tests were usually normal. Assisted zona hatching Autologous endometrial coculture Cytoplasmic transfer Embryo transfer Gestational carrier In vitro maturation Intracytoplasmic sperm injection Oocyte selection Ovarian hyperstimulation Preimplantation genetic diagnosis Snowflake children Transvaginal ovum retrieval Zygote intrafallopian transfer. Sometimes they are serious, most of the time they are not. From Wikipedia, the free encyclopedia. Clomiphene may also be used for other conditions in both females and males as determined by your doctor. Clomifene was approved for medical use in the United States in A causal relationship between treatment with clomiphene citrate and ovarian cancer has not been established. Along with its needed effects, a medicine may cause some unwanted effects. International Drug Price Indicator Guide. A locked cupboard at least one-and-a-half metres above Serpohene ground is Seropheje good Serophenee to store medicines. We comply with the HONcode standard for trustworthy health information - Seropheen here. Archived from the original on October 6, Serophene by Pharmascience is no longer being manufactured for sale in Canada. All rights reserved. A woman is most likely to become pregnant if she has intercourse within the 24 hours after detecting Seropheje LH surge. Sources: See template. Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. Talk to your doctor about whether you should continue breast-feeding. Until you know how Serophene will affect you, do not drive or perform any task that may be considered unsafe. Some people may experience side effects other than those listed. The side effects listed below are not experienced by everyone who takes this medication. It may also cause some people to become dizzy or lightheaded. Heat and dampness can destroy some medicines. Along with its needed effects, a medicine may cause some unwanted effects. The most serious side effect of this drug is its tendency to cause Serophene birth defects. Since estrogen can no longer effectively exert negative feedback on the hypothalamus, GnRH secretion becomes more rapidly pulsatile, which results in increased pituitary gonadotropin release. Also tell them about any supplements you take. The presence of other medical problems may affect the use of this medicine. Antiandrogens e. By using this site, you agree to the Terms of Use and Privacy Policy. This material is provided for educational purposes only and is not intended for Serophene advice, diagnosis Serophenw treatment. Monthly newsletter. It is important that intercourse take place at the correct time to Seropnene you the best chance of becoming pregnant. The risk of some birth Serophend goes up substantially—sometimes by as much as percent—after being exposed to Serophene. Serophfne usual dose is 1 tablet every day for 5 days. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines. However, you should try to take the tablets at the same time each day. This will usually be associated with severe ovarian hyperstimulation syndrome OHSS. Daily news summary. Before you take SEROPHENE When you must not take it Do not take SEROPHENE if: you are pregnant you are breastfeeding you have liver disease or a history of liver disease you have abnormal menstruation or vaginal bleeding you have enlarged ovaries or ovarian cysts not due to polycystic ovary disease you are suffering from depression you have a blood clot you have problems with your eyesight you have uncontrolled thyroid disease you have problems with your adrenal gland you have a pituitary tumour you have hormone-dependent tumours. If enlargement of the ovary occurs, additional clomiPHENE citrate therapy should Setophene be given Serophene the ovaries have returned to pretreatment size, and the dosage or duration of the next course should be reduced. Myths: Pneumococcal disease. Seophene reproductive technology. Serophene by Pharmascience is no longer being manufactured for sale in Canada. This is a rare but potentially serious side effect of infertility treatment. In addition, the following symptoms have been reported in association with this syndrome: pericardial effusion, anasarca, hydrothorax, acute abdomen, hypotension, renal failure, pulmonary edema, intraperitoneal and ovarian hemorrhage, deep venous thrombosis, torsion of the ovary, and acute respiratory distress. However, if you do not fall pregnant after 3 treatment cycles, further treatment is not usually recommended. Selective estrogen receptor modulator ; Progonadotropin. Retrieved 21 April Do not try to make up for missed doses by taking more than one dose at a time. Do not dispose of medications in wastewater e. Instructions This medication is typically used only once a day. Check with your doctor if you notice any symptom that worries you while you are taking this medication. It is recommended not to use this medication for more than 3 cycles of treatment. Be sure to ask your doctor any questions you might have. Women should notify their doctor of any abdominal or pelvic pain, weight gain, discomfort, or bloating after taking clomiphene. BioMed Research International. Fall Other side effects not listed may also occur in some patients.
Common use

Serophene is an non-steroid anti-estrogen. Mechanism of its action consists in a specific binding with receptor for estrogen in ovary and hypophis. In patients with low estrogen levels in organism it causes estrogen effect and in ones with high estrogen levels it causes anti-estrogen effect. Its small doses increase secretion of gonadotropins (prolactin, Follicle stimulating hormone, FSH and interstitial cell-stimulating hormone), stimulates ovulation; in large doses slows secretion of gonadotropins. In the whole action of Serophene consists in stimulation of ovulation to occur and prepares the body for pregnancy. This medication may be used for male patients with infertility caused by low production of sperm.

Dosage and direction

Serophene is administered to stimulate ovulation 50 mg 1 time a day at bedtime, starting from 5th day of the menstrual cycle during 5 days (in the absence of the cycle - at any time). In case of no effect (ovulation does not occur within 30 days) increase the dose to 150 mg / day or lengthen the course to 10 days. Take exactly as prescribed, do not take the medication in larger quantities.


Before to take Serophene notify your doctor if you have ever had any allergic reaction to clomiphene, liver diseases, mental depression, thrombophlebitis. This drug may cause vision problems, dizziness, or lightheadedness, be especially attentive if you need driving or operating machinery which requires high concentration of attention.


Hypersensitivity, liver or kidney failure, metrorrhagia of unknown etiology, ovarian cysts, neoplasms of genital organs, tumor or hypofunction of the hypophysis, endometriosis, ovarian failure together with hyperprolactinaemia, pregnancy.

Possible side effect

Together with allergy symptoms such as swelling of lips, tongue, or face or hives in some patients may appear the following conditions: ovarian enlargement presenting as abdominal or pelvic pain, flushing, nausea, vomiting, or diarrhea, blurred vision, headache, abnormal uterine bleeding.

Drug interaction

Inform your doctor and laboratory operators about all medications and herbal products you are taking if you are treated with Serophene.

Missed dose

If you missed a dose take it as soon as you remember, but not if it is almost time of the next intake by your schedule. If so skip the missed dose. Do not try to make up a missed dose by taking an extra one.


If you suspect that you took too much of the medication seek for immediate medical attention.


Store Serophene in a dry place away from sunlight at room temperature between 15-30 C (59-86 F).


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. The specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Thyroid problems

Thyroid gland a gland of the organism located in the front part of the neck. The whole gland weights 25-30g. It works by producing 4 hormones amongst which the major are T4 Thyroxin and T3 Tri-iodothyronine. Also the gland produces Calcitonin a biologically active substance that regulates the Ca2+ metabolism in the body.

The thyroid gland, pituitary gland and hypothalamus work as one regulatory system. There are different types of thyroid gland dysfunctions for example:

  • Hypothyroidism A dysfunction which manifests in decreased production or inability to produce thyroid hormones. All the metabolism processes in the organism are slowed down. The causes of the disorder might be autoimmune thyroiditis, therapy with radioactive Iodine, hereditary disorders.
  • Hyperthyroid an excess in production of thyroid hormones. The disorder leads to an increase in the organisms metabolism speed. The causes of the disorder might be: benign tumors, when the gland is not controlled by the pituitary gland, autoimmune processes Graves's disease. The symptoms of the hyperfunction may lead to thyrotoxic crisis or thyroid storm a severe condition which affects the main organism functions and in turn may leading to coma and death.
  • Another dysfunction of the thyroid gland is goiter which is caused by iodine insufficiency, followed by an increase in size of the thyroid gland which may lead to hyper- or hypothyroidism.

If you feel that some of the following may be applied to youthen a possibility of the thyroid disorder exists:

  • Fatigue, especially in the morning and less in the evening
  • Changes in weight, especially around the abdomen
  • Depression and melancholy
  • Increased levels of cholesterol
  • Spasms and muscle contractions
  • Constipation
  • Arthritis and joint pain
  • Bad memory and other neurological

All of the above may signal a possible thyroid disorder. It would be safe to consult your doctor and measure the levels of the T4 and T3 hormones in the blood.